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Research Use Only. This product is intended exclusively for laboratory research purposes. Not for human consumption, medical use, or veterinary use. No dosing or administration instructions are provided.
Epitalon (Epithalon) | Research Grade | 10mg
$74.99
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) designed for laboratory research into telomerase activity modulation, gene expression regulation, and pineal peptide biology. ≥99% purity, HPLC-verified, with independent third-party Certificate of Analysis. For laboratory research use only. Not for human consumption.
50 in stock
≥99% PURE (HPLC)
THIRD-PARTY TESTED
COA INCLUDED
USA MANUFACTURED
THIRD-PARTY TESTED
COA INCLUDED
USA MANUFACTURED
Product Overview
Epitalon (Epithalon) is a synthetic tetrapeptide consisting of four amino acids (Ala-Glu-Asp-Gly, single-letter code AEDG), originally derived from epithalamin, a natural polypeptide complex from the pineal gland. Epitalon serves as a biological research tool for investigating telomerase activity modulation, gene expression regulation, and pineal neuroendocrine signaling in controlled laboratory settings.
Supplied as a lyophilized research reagent at ≥99% purity. Every order is accompanied by an independent third-party verified Certificate of Analysis with a unique authentication key for direct lab verification.
Research Applications
Epitalon is intended for use in qualified laboratory research environments, including:
- Telomerase activity and telomere maintenance research
- Gene expression profiling and epigenetic mechanism studies
- Pineal gland peptide biology and neuroendocrine signaling
- Cellular senescence and stress-response models
- Peptide-DNA interaction and chromatin structure research
Mechanism of Action
Epitalon activates human telomerase reverse transcriptase (hTERT) gene expression and enzymatic activity, inducing telomere elongation in human somatic cells in cultured cell models. As a short peptide bioregulator, Epitalon binds directly to complementary double- and single-stranded DNA promoter regions and histone proteins, promoting chromatin decondensation, reactivation of silent ribosomal genes, and site-specific transcription initiation. Epitalon also modulates pinealocyte secretory activity, supporting baseline circadian regulation of pineal peptide production and melatonin synthesis pathways in cellular and animal tissue models.
Product Specifications
| Specification | Value |
|---|---|
| Compound | Epitalon (Epithalon) |
| Compound Name | L-alanyl-L-α-glutamyl-L-α-aspartyl-glycine |
| CAS Number | 307297-39-8 |
| Amino Acid Sequence | Ala-Glu-Asp-Gly (AEDG) |
| Molecular Formula | C₁₄H₂₂N₄O₉ |
| Molecular Weight | 390.35 g/mol |
| Peptide Class | Synthetic tetrapeptide (pineal bioregulator) |
| Purity | ≥99% (HPLC-verified) |
| Physical Form | Lyophilized powder |
| Appearance | White to off-white lyophilized powder |
| Net Content | 10mg |
| Manufacturing | USA-manufactured |
Quality & Testing
Every batch undergoes independent third-party laboratory testing to verify purity, identity, and quality. Each order includes:
- Certificate of Analysis (COA) with unique batch number
- Independent third-party verification key — verifiable directly through the testing laboratory’s online portal
- HPLC purity analysis
- Mass spectrometry identity confirmation
- Endotoxin and microbial contamination screening
“Trust is the most important compound in our catalog.” Every claim about purity, identity, and quality is independently verifiable — not just stated on a label.
Storage & Handling
- Product is supplied in a sterile vial — maintain sterility until use
- Store lyophilized material at -20°C upon receipt
- Protect from moisture and direct light
- Allow vial to equilibrate to room temperature before opening
- Handle in accordance with your institution’s laboratory safety protocols
- Use appropriate personal protective equipment when handling
Frequently Asked Questions
What is Epitalon?
Epitalon (Epithalon) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly (AEDG). It was originally derived from epithalamin, a polypeptide complex from the pineal gland. Epitalon is used as a laboratory research tool for studying telomerase activity, gene expression regulation, and pineal neuroendocrine signaling.
What is the CAS number for Epitalon?
The CAS registry number for Epitalon (free peptide base) is 307297-39-8.
What is the amino acid sequence of Epitalon?
Epitalon is a tetrapeptide consisting of four amino acids: Alanine-Glutamic Acid-Aspartic Acid-Glycine (Ala-Glu-Asp-Gly, or AEDG in single-letter code).
What is telomerase?
Telomerase is a ribonucleoprotein enzyme that adds telomere repeat sequences to the ends of chromosomes. It consists of a reverse transcriptase catalytic subunit (hTERT) and an RNA template component (TERC). Epitalon has been shown to activate hTERT gene expression in cell culture research models.
How should Epitalon be stored?
Store the lyophilized material at -20°C upon receipt. Protect from moisture and direct light. Allow the vial to equilibrate to room temperature before opening.
Is a Certificate of Analysis included?
Yes. Every order includes a batch-specific Certificate of Analysis with an independent third-party verification key, verifiable directly through the testing laboratory’s online portal.
For laboratory research use only. Not for human consumption.
This product is a laboratory research reagent and is not intended for human consumption, therapeutic use, diagnostic procedures, or veterinary applications. This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. Researchers must ensure compliance with all applicable institutional, local, and federal regulations prior to use. Must be 21 or older to purchase.
| Weight | 0.1 lbs |
|---|---|
| Dimensions | 4 × 2 × 2 in |
| CAS Number | 307297-39-8 |
| Purity | ≥99% |
| Net Content | 10mg |
| Form | Lyophilized |
| Storage Temperature | -20°C |
Certificate of Analysis
COA data for the current batch is being processed. Please check back shortly or contact us with the lot number from your packaging.
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Product Disclaimer
For laboratory research use only. Not for human consumption, medical use, or veterinary use. These products have not been evaluated by the FDA. They are not intended to diagnose, treat, cure, or prevent any disease.
PepperCo Research products are manufactured and tested in accordance with industry standards. All products are accompanied by a Certificate of Analysis (COA) verifying purity and identity. Products are sold without instructions for use, administration, or preparation.
By purchasing, the buyer confirms they are 21 years of age or older and accepts full responsibility for the safe and proper handling of all materials in a laboratory research setting.
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