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Research Use Only. This product is intended exclusively for laboratory research purposes. Not for human consumption, medical use, or veterinary use. No dosing or administration instructions are provided.
Selank (Tuftsin Analogue) | Research Grade | 5mg
$49.99
Synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) and tuftsin analogue designed for laboratory research into neuropeptide receptor signaling and GABAergic pathway modulation. ≥99% purity, HPLC-verified, with independent third-party Certificate of Analysis. For laboratory research use only. Not for human consumption.
50 in stock
≥99% PURE (HPLC)
THIRD-PARTY TESTED
COA INCLUDED
USA MANUFACTURED
THIRD-PARTY TESTED
COA INCLUDED
USA MANUFACTURED
Product Overview
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) fragment of immunoglobulin G. Selank serves as a biological research tool for investigating neuropeptide receptor signaling pathways, GABAergic system modulation, and enzyme inhibition kinetics in controlled laboratory settings.
Supplied as a lyophilized research reagent at ≥99% purity. Every order is accompanied by an independent third-party verified Certificate of Analysis with a unique authentication key for direct lab verification.
Research Applications
Selank is intended for use in qualified laboratory research environments, including:
- Neuropeptide receptor signaling and GABAergic pathway modulation research
- Enkephalin-degrading enzyme inhibition kinetics and characterization
- Gene expression profiling in neuronal cell models
- GABA receptor allosteric modulation and binding studies
- Peptide-based enzyme inhibitor pharmacology and SAR research
Mechanism of Action
Selank is a synthetic heptapeptide and analogue of tuftsin (Thr-Lys-Pro-Arg), a naturally occurring tetrapeptide fragment of immunoglobulin G. Research indicates that Selank modulates the GABAergic signaling pathway, where it acts as a positive allosteric modulator of GABA binding at GABA-A receptors. Selank also inhibits enkephalin-degrading enzymes (enkephalinases), with an IC₅₀ of approximately 20 μM. Additionally, Selank influences the expression of genes involved in neurotransmission in neuronal cell models. These molecular activities make Selank a research tool for studying neuropeptide receptor pharmacology and enzyme inhibition mechanisms.
Product Specifications
| Specification | Value |
|---|---|
| Compound | Selank |
| Compound Name | L-Threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline |
| CAS Number | 129954-34-3 |
| Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP, heptapeptide) |
| Molecular Formula | C₃₃H₅₇N₁₁O₉ |
| Molecular Weight | 751.9 g/mol |
| Peptide Class | Synthetic heptapeptide (tuftsin analogue) |
| Purity | ≥99% (HPLC-verified) |
| Physical Form | Lyophilized powder |
| Appearance | White to off-white lyophilized powder |
| Net Content | 5mg |
| Manufacturing | USA-manufactured |
Quality & Testing
Every batch undergoes independent third-party laboratory testing to verify purity, identity, and quality. Each order includes:
- Certificate of Analysis (COA) with unique batch number
- Independent third-party verification key — verifiable directly through the testing laboratory’s online portal
- HPLC purity analysis
- Mass spectrometry identity confirmation
- Endotoxin and microbial contamination screening
“Trust is the most important compound in our catalog.” Every claim about purity, identity, and quality is independently verifiable — not just stated on a label.
Storage & Handling
- Product is supplied in a sterile vial — maintain sterility until use
- Store lyophilized material at -20°C upon receipt
- Protect from moisture and direct light
- Allow vial to equilibrate to room temperature before opening
- Handle in accordance with your institution’s laboratory safety protocols
- Use appropriate personal protective equipment when handling
Frequently Asked Questions
What is Selank?
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from tuftsin, a naturally occurring tetrapeptide fragment of immunoglobulin G. It serves as a research tool for studying neuropeptide receptor signaling, GABAergic pathway modulation, and enkephalin-degrading enzyme inhibition.
What is the CAS number for Selank?
The CAS registry number for Selank is 129954-34-3.
What is the amino acid sequence of Selank?
Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (single-letter code: TKPRPGP). It is a synthetic analogue of tuftsin (Thr-Lys-Pro-Arg), extended with Pro-Gly-Pro at the C-terminus.
What is tuftsin?
Tuftsin (Thr-Lys-Pro-Arg) is a naturally occurring tetrapeptide derived from the Fc region of immunoglobulin G. It plays a role in immune cell signaling. Selank was designed as a tuftsin analogue to study neuropeptide receptor signaling and enzyme inhibition pathways.
How should Selank be stored?
Store the lyophilized material at -20°C upon receipt. Protect from moisture and direct light. Allow the vial to equilibrate to room temperature before opening.
Is a Certificate of Analysis included?
Yes. Every order includes a batch-specific Certificate of Analysis with an independent third-party verification key, verifiable directly through the testing laboratory’s online portal.
For laboratory research use only. Not for human consumption.
This product is a laboratory research reagent and is not intended for human consumption, therapeutic use, diagnostic procedures, or veterinary applications. This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. Researchers must ensure compliance with all applicable institutional, local, and federal regulations prior to use. Must be 21 or older to purchase.
| Weight | 0.1 lbs |
|---|---|
| Dimensions | 4 × 2 × 2 in |
| CAS Number | 129954-34-3 |
| Purity | >=99% |
| Net Content | 5mg |
| Form | Lyophilized |
| Storage Temperature | -20C |
Certificate of Analysis
COA data for the current batch is being processed. Please check back shortly or contact us with the lot number from your packaging.
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Product Disclaimer
For laboratory research use only. Not for human consumption, medical use, or veterinary use. These products have not been evaluated by the FDA. They are not intended to diagnose, treat, cure, or prevent any disease.
PepperCo Research products are manufactured and tested in accordance with industry standards. All products are accompanied by a Certificate of Analysis (COA) verifying purity and identity. Products are sold without instructions for use, administration, or preparation.
By purchasing, the buyer confirms they are 21 years of age or older and accepts full responsibility for the safe and proper handling of all materials in a laboratory research setting.
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