Snap-8 (Acetyl Octapeptide-3) | Research Grade | 10mg

Product Overview

Snap-8 (Acetyl Octapeptide-3) is a synthetic octapeptide developed for laboratory investigation of SNARE complex assembly and neurotransmitter release mechanisms. As an N-terminal analog of SNAP-25 (Synaptosomal-Associated Protein, 25kDa), Snap-8 serves as a biological research tool for studying presynaptic membrane fusion dynamics, neuromuscular junction signaling, and synaptic vesicle exocytosis pathways.

Supplied as a lyophilized research reagent at ≥99% purity. Every order is accompanied by an independent third-party verified Certificate of Analysis with a unique authentication key for direct lab verification.

Research Applications

Snap-8 is intended for use in qualified laboratory research environments, including:

• SNARE complex assembly and disassembly studies
• Neuromuscular junction signaling pathway research
• Synaptic vesicle exocytosis investigation
• Presynaptic membrane fusion dynamics
• Cell signaling and protein interaction model development (in vitro and in vivo)

Mechanism of Action

Acetyl Octapeptide-3 is a truncated analog of the SNAP-25 N-terminal domain, extended by two additional amino acid residues (Ala-Asp) relative to the related Acetyl Hexapeptide-3. In biological research models, Snap-8 interacts with the SNARE (Soluble NSF Attachment Protein Receptor) complex, modulating the protein-protein interactions required for synaptic vesicle fusion with the presynaptic membrane. This mechanism has been characterized in published peer-reviewed research as a model for studying neurotransmitter release regulation in controlled laboratory settings.

Product Specifications

Quality & Testing

Every batch of Snap-8 undergoes independent third-party laboratory testing to verify purity, identity, and quality. Each order includes:

• Certificate of Analysis (COA) with unique batch number
• Independent third-party verification key — verifiable directly through the testing laboratory’s online portal
• HPLC purity analysis
• Mass spectrometry identity confirmation
• Endotoxin and microbial contamination screening

Storage & Handling

• Product is supplied in a sterile vial — maintain sterility until use
• Store lyophilized material at -20°C upon receipt
• Protect from moisture and direct light
• Allow vial to equilibrate to room temperature before opening
• Handle in accordance with your institution’s laboratory safety protocols
• Use appropriate personal protective equipment when handling

Frequently Asked Questions