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What Is Selank?
Selank is a synthetic heptapeptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, developed at the Institute of Molecular Genetics in Moscow as a shortened analog of the naturally occurring peptide tuftsin. It is studied in laboratory research for neuromodulatory effects and cognitive function in animal research models, with published data suggesting modulation of monoamine neurotransmitter systems and brain-derived neurotrophic factor (BDNF).
How Is Selank Handled and Reconstituted in the Laboratory?
PepperCo Research supplies Selank as a lyophilized (freeze-dried) reagent in a sterile sealed vial at ≥ 99% HPLC purity. Proper handling and reconstitution are essential to preserve peptide integrity for in vitro research applications.
- Storage (lyophilized): Store at -20°C in the original sealed vial, protected from light and moisture. Under these conditions, lyophilized peptide reagent is generally stable for up to 24 months.
- Reconstitution: Allow the sealed vial to equilibrate to room temperature before opening. Reconstitute using a sterile laboratory-grade solvent appropriate for the intended in vitro application. Gentle swirling (not vortexing) is recommended to dissolve the lyophilized material fully.
- Storage (reconstituted): Once in solution, aliquot into sterile microcentrifuge tubes to avoid repeated freeze-thaw cycles. Store aliquots frozen at -20°C and use within the timeframe validated by the researcher’s stability protocol.
- Handling: Use aseptic technique throughout. Avoid repeated exposure to room temperature. Always refer to the lot-specific Certificate of Analysis (COA) for batch-level purity and identity data.
Reconstitution Best Practice
All PepperCo Research peptide reagents are supplied lyophilized and are intended for in vitro laboratory research only. Researchers should select solvents and concentrations appropriate to their specific experimental protocols. Not for human consumption or therapeutic application.
What Quality and Testing Standards Apply to Selank Reagent?
Every batch of Selank reagent from PepperCo Research undergoes rigorous quality verification to support reproducible laboratory research:
- HPLC Purity Testing: Each lot is analyzed by High-Performance Liquid Chromatography to confirm purity of ≥ 99%, ensuring minimal residual content from synthesis byproducts.
- Mass Spectrometry: Molecular weight and identity are confirmed by mass spectrometry, verifying the expected mass of approximately 751.87 Da for the intact peptide.
- Third-Party Verification: Independent third-party laboratory testing is conducted to provide an unbiased quality assessment beyond the manufacturer’s in-house results.
- Certificate of Analysis: A lot-specific COA accompanies every vial, documenting purity, identity, and appearance for the researcher’s records.
- Sterile Packaging: Peptide reagent is lyophilized and sealed in sterile vials under controlled conditions to maintain integrity from production to the laboratory bench.
Selank Reagent — Available Now
Lyophilized Selank (≥ 99% purity) in sterile vials. Full COA and third-party test results included.
Frequently Asked Questions
What is Selank?
Selank is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, developed at the Institute of Molecular Genetics in Moscow as a shortened analog of the naturally occurring peptide tuftsin. It is studied in laboratory research for neuromodulatory and cognitive effects in animal models.
How does Selank relate to tuftsin?
Tuftsin is a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) involved in immune modulation. Selank extends this sequence with three additional amino acids (Pro-Gly-Pro), producing a heptapeptide analog that has been studied for both neuromodulatory and immunomodulatory activity in preclinical models. The extended sequence is associated with greater metabolic stability than the parent peptide.
What is the molecular weight and CAS number of Selank?
Selank has a molecular formula of C33H57N11O9 and a molecular weight of approximately 751.87 g/mol. The CAS number assigned to Selank is 129954-34-3.
How should Selank reagent be stored in the laboratory?
Lyophilized Selank reagent should be stored at -20°C in its sealed sterile vial, protected from light and moisture. Once reconstituted with a suitable laboratory solvent, the solution should be aliquoted and stored frozen to preserve peptide integrity for in vitro research applications.